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For several years, Pradaxa, Elliquis, and Xarelto have had the market cornered on sales of New Oral Anticoagulants (NOACs) as treatment for patients who suffer from a serious medical condition known as atrial fibrillation (Afib). NOACs are an entirely new class of drugs designed to replace conventional blood thinners, such as Coumadin (Warfarin).

money-trading-1-1415239-mHowever, Daiichi Sankyo has recently entered the market with its own NOAC product under the name Savaysa. The company has high hopes for Savaysa sales, given that it recently lost its patent for Benicar, according to a recent news article from Fierce Pharma. Benicar, which will soon be available as a generic, is responsible for around 27 percent of Daiichi sales, so this loss will hurt. The company is hoping to make up for that loss with sales of their new drug, Savaysa, but they are running into some stumbling blocks. Continue reading

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Three dimensional, or 3D, printing is much more impressive than most people realized when they first heard of the process. A 3D printer can function in one of two main ways. In one type of 3D printer, the printer takes a computer rendered image and then cuts out a design from a block of material, usually made out of some type of polymer. This design works similar to high priced C&C routers and is known as a destructive construction process. The reason it is called a destructive process is because, much a like a sculptor working with a block of marble, material is chipped away until the intended design is formed.

knee-x-ray-1-391480-mThe really impressive form of 3D printing involves a process where the print heads create the item through emitting layer after layer of material until the design is complete. Not only can these designs be completely customized one at a time, because no construction run is required, they can also create interlocking pieces at the same time. For example, a 3D printer can print a series of interlocking rings without the need for any break in the metal or joint to link the rings, since they were constructed that way. Continue reading

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New Oral Anticoagulants (NOACs) are big money for drug companies and marketing partners pushing four different medications currently on the market. One of the four drugs is Eliquis, manufactured by Bristol-Myers Squibb (BMS), and, according to recent article from Forbes, the drugmaker has a lot riding on Eliquis sales.

tablet-931317-mSpecifically, Forbes estimates that around a quarter of BMS’s total value is directly tied to Eliquis. In other words, the future of Eliquis can make or break the economic viability of the company. Continue reading

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NBC Nightly News recently aired a report that has raised significant questions regarding the safety of a medical device known as an IVC filter. Specifically, the Recovery IVC filters made by BARD have been connected to at least 300 adverse events, including 27 deaths.chestxray

The report was just the first in a series the station plans to air in the coming days on these medical devices, which are implanted in thousands of Americans to reduce the risk of blood clots. It’s a 1.5-inch piece of metal that is inserted into the vena cava, a major vein, and has the ability to block blood clots from traveling to the heart or the lungs, where they have the potential to be fatal.

Journalists disclosed a 2004 confidential study commissioned by the maker of the product, C.R. Bard, in which it reveals this particular product had a higher rate of injury and fatalities when compared to those who used competitor product. These devices appear to be perforating, migrating, breaking or, in some cases, actually causing clogs rather than preventing clots. Despite this, Bard, a multinational product manufacturer, did not recall its product.

Despite the fact that researchers who conducted the study clearly stated further investigation of this matter was “urgently warranted.” Continue reading

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For decades, Warfarin (Coumadin) has been the gold standard drug for atrial fibrillation (Afib) patients to avoid being at a higher risk for stroke and other potentially deadly medical conditions like a pulmonary embolism (PE).

courtroom-1-1207444-mWhile Warfarin is considered relatively safe, it does require patients to have frequent monitoring by their physicians to make sure the dosage is correct. This means the patients need to regularly have blood taken to determine how the blood thinner is working. If the dosage is off, it can result in serious medical conditions, including bleeding disorders. While this is a risk, with proper monitoring, it should not occur, and, if it does occur, doctors can often reverse the effects of the drug. Continue reading

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Eliquis, manufactured by Bristol-Myers Squibb (BMS) and Pfizer, is now claiming its new oral anticoagulant (NOAC) is safer than other NOACs (Xarelto, Pradaxa, and Savaysa), according to a recent news article from Medpage Today.

untitled-1238929-mBased upon a recent study, paid for by BMS and Pfizer, their drug, Eliquis, was shown to cause less major bleeding cases in patients with non-valvular atrial fibrillation (Afib) that patients taking Pradaxa, or Xarelto. Savaysa was not specifically included in this study because the United States Food and Drug Administration (FDA) only recently approved it for sale on the market. Continue reading

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Xarelto, Eliquis, Pradaxa, and the newly-marketed Savaysa are all members of a class of drugs known as New Oral Anticoagulants (NOACs). They are all advertised as a safer and easier to use alternative to Warfarin (Coumadin), which has been the long-standing drug prescribed to patients who suffer from an irregular heartbeat condition known as atrial fibrillation (Afib).

pills-1023897-mAfib patients require either a blood thinner like Warfarin or an oral anticoagulant like Xarelto to decrease the risk they will develop a serious clotting disorder.   If patient develops clots deep within the veins of his or her legs, which is known as deep vein thrombosis (DVT), the clots can break loose and travel to the lungs, where they can puncture the tissue, causing a potentially deadly condition known as pulmonary embolism (PE). The clots can also block blood flow to the brain, which results in a stroke. Continue reading

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Every year, we see more advancements in medicine, including development of newer high-tech medical devices like those used in knee replacement surgery. According to a recent news feature form ABC 6, a new device works much “like a GPS” during total knee replacement surgery to help align a new artificial joint.

medical-instruments-3-1033916-mProper and secure alignment is essential in the long-term success of a total knee replacement. No matter how skilled a surgeon may be, if the artificial knee joint or the surgical cutting guide has been defectively designed, as we have seen in many cases, there is significant risk the knee will not be aligned properly. Even if proper alignment is established during surgery, manufacturing defects can cause the knee joint to shift out of alignment.   An artificial knee out of alignment can lead to significant pain and suffering and failure of the device. Continue reading

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For over a year, we have been hearing a great deal about potential benefits of minimally invasive knee replacement surgery. However, according to a recent news release from the world-renowned Cleveland Clinic, minimally invasive knee surgery may not be right for every patient choosing to undergo elective total knee replacement.

hospital-hand-1100587-mIf you are speaking with an orthopedic surgeon about having a total knee replacement, there is a decent chance you are discussing the risks and benefits of having the minimally invasive procedure. As the name implies, minimally invasive knee replacement involves using a smaller incision than in traditional or “open” total knee replacement and does not involve cutting as much muscle or other tissue surrounding the knee joint. This can result in a hospital stay that is shorter, as well as a shorter recovery period. There is also less blood loss, which can make the surgery safer in many cases. For these reasons, the Cleveland Clinic recommends you discuss this option with your surgeon. Continue reading

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According to a recent news article from CBS, a World War II veteran who served as a fighter pilot was recently attacked, and the alleged attacker was his 63-year-old son. Authorities say victim’s son has been verbally abuse to victim in the past, and, on this occasion, allegedly punched his father’s dog, causing the two men to argue. During the course of their argument, defendant allegedly punched his father inside father’s home, causing him to fall to the floor. When he hit the floor, he suffered various injuries, including a broken hip.

ww2-b17-bomber-5-1624078At this point, sheriff’s deputies say defendant left the home with his father lying in pain on the floor without offering any assistance or calling for help. When other family members found victim, they called 911. Police and paramedics arrived at the home. Police obtained an arrest warrant for defendant and arrested him on charges of aggravated battery of a person over the age of 65. This is known as a sentencing enhancement, which is added to a charge when the victim is a child, elderly, or physically or mental disabled. It can add years to the sentence and add mandatory minimum prison time, as well. Defendant is being held on $100,000 bond and is currently in a county detention center. Continue reading

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